GLP-1 & Metabolic
RS-SEM-1 5–50 mg
Research use only
31-residue chain, 4113.58 g/mol, CAS 910463-68-2. 4 current lot certificates on file; lot SEM5-0803 measured 99.75% by RP-HPLC (214 nm) on 17 August 2026.
Strength
$70.00
per vial · $14.00 per mg
Prices shown are what you pay at checkout, with no account needed. Buyers with a Restate account may see their own pricing when signed in.
1
Measured on lot SEM5-0803
17 August 2026- Identity
- RS-SEM-1
- Content
- 5.19 mg
- Overall Purity
- 99.75%
- Endotoxin
- <0.05 EU/mL
- Heavy Metals
- <0.01 ppm
Reported by Bioviridian Inc. on certificate COA7591. The vial is labelled 5 mg; the laboratory quantified 5.19 mg. 4 current lots are on file and the figures differ between them — match the lot number on your vial.
A lot’s own chromatogram is printed on its Certificate of Analysis.
- Form
- Lyophilized powder vial
- Documentation
- 4 current lot certificates on file. View lot documentation
- Shipping
- Ships from the US in protective packaging with tracking
What RS-SEM-1 is
NN9535 is a synthetic long-acting GLP-1 receptor agonist and analog of human GLP-1 (CAS 910463-68-2, C187H291N45O59, 4113.58 g/mol). It is a 31-residue peptide with Aib at position 2 and Lys26 conjugated to a gamma-Glu-(AEEA)2-C18 diacid, with a C-terminal carboxylate. Studied in metabolic research models. Supplied as a lyophilized powder; purity by HPLC with a certificate of analysis for every lot.
RS-SEM-1 in the literature
A 31-residue analogue of human GLP-1, NN9535 is a synthetic long-acting GLP-1 receptor agonist (CAS 910463-68-2, C187H291N45O59, 4113.58 g/mol). Position 2 carries Aib, Lys26 is conjugated to a gamma-Glu-(AEEA)2-C18 diacid, and the chain ends in a free carboxylate. In this catalogue it is the single-receptor reference point for the incretin class: LY3298176 adds GIP activity and LY3437943 adds glucagon, whereas NN9535 is examined in metabolic research models as a GLP-1 receptor ligand alone. How the three differ residue by residue is set out in NN9535, LY3298176 and LY3437943: A Structural Comparison; the chemistry of the backbone itself is in The Peptide Bond.
RS-SEM-1 in the catalogue
RS-SEM-1 is the most widely sized item in GLP-1 & Metabolic, with five vials: 5 mg at $70.00 ($14.00/mg), 10 mg at $86.80 ($8.68/mg), 20 mg at $151.20 ($7.56/mg), 30 mg at $182.00 ($6.07/mg) and 50 mg at $224.00 ($4.48/mg). The 5 mg vial is the entry size and the 50 mg vial is the lowest per milligram. It is not bundled, and RS-AMR1 is the product buyers most frequently add to the same order. Research use only, for buyers aged 21 or over, applies to every sale; you can view all four published certificates before deciding on a size.
On the certificate
On 17 August 2026 Bioviridian Inc. tested lot SEM5-0803, the 5 mg strength of RS-SEM-1, and recorded 99.75% purity on certificate COA7591. That sheet reports identity, content, overall purity, endotoxin and heavy metals, and all four certificates issued for the product are current. RS-SEM-1 is a lyophilised powder; the catalogue record asks for −20°C storage with protection from light and moisture, and refrigeration once the material is in solution. The certificate matching the lot shipped is included in the box and kept in the buyer's account.
RS-SEM-1 specification
- Purity
- ≥99% by HPLC · certificates on file
- CAS number
- 910463-68-2
- Molecular formula
- C187H291N45O59
- Molecular weight
- 4113.58 g/mol
- Amino acid count
- 31
- Sequence
- 31-residue GLP-1 receptor agonist analog with Aib at position 2 and Lys26 conjugated to γGlu-(AEEA)2-C18 diacid; C-terminal carboxylate (full sequence per COA).
- Synonyms
- GLP-1 receptor agonist
- Physical form
- Lyophilized powder
- Solubility
- Soluble in bacteriostatic water; consult the product COA for specific solvent recommendations.
- Storage
- Store lyophilized at -20°C; protect from light and moisture. Reconstitute with bacteriostatic water; store reconstituted material refrigerated and use per laboratory protocol.
Lot documentation for RS-SEM-1
Each lot has its own Certificate of Analysis. Match the lot number printed on your vial to open the certificate for it.
StrengthLotPurityTestedStatusCertificate
Safety Data Sheet SDS-AP-NN9535 · v1.0
Open the safety data sheet (PDF)Reading on RS-SEM-1
Complete the order
Reconstitution solution and bacteriostatic water, ready in the same order.
Questions about RS-SEM-1
Is NN9535 third-party tested?
Yes. Every lot of NN9535 (CAS 910463-68-2) is tested for identity and purity to ≥99% by HPLC, and a lot-matched Certificate of Analysis is available for each batch.
Can I review the Certificate of Analysis before ordering?
Yes. The certificates for current lots of RS-SEM-1 are listed on this page under Lot documentation, each with the identity, content and purity results the laboratory reported. If the lot or strength you need is not listed, ask support what is on file before you order.
Who can order NN9535 10 mg?
Restate Health supplies qualified researchers, laboratories, and other qualified purchasers only — for research use only. Accounts are verified before ordering is enabled, and this product is not sold to the general public.
How should it be stored and handled?
Supplied as lyophilized powder. Store lyophilized at -20°C; protect from light and moisture. Reconstitute with bacteriostatic water; store reconstituted material refrigerated and use per laboratory protocol. Soluble in bacteriostatic water; consult the product COA for specific solvent recommendations.
How quickly does it ship?
Orders confirmed before 12pm CT typically ship the same business day from our U.S. facility with tracking. Restate Health can confirm current lead time and cold-chain handling for your account.
What did the laboratory measure on the current lot of RS-SEM-1?
Lot SEM5-0803 (5 mg) was tested on 17 August 2026 by Bioviridian Inc. and reported identity RS-SEM-1 (LC-MS/MS), content 5.19 mg (HPLC Quantitation), overall purity 99.75% (RP-HPLC (214 nm)), endotoxin <0.05 EU/mL (<USP85>), heavy metals <0.01 ppm (<USP232>). The certificate is COA7591 and is published in full on this page. 4 current lots are on file and the figures differ between them, so read the certificate for the lot number printed on your vial.
What are the chemical identifiers for RS-SEM-1?
For RS-SEM-1, its CAS number is 910463-68-2, its molecular formula is C187H291N45O59, its molecular weight is 4113.58 g/mol, it is a 31-residue chain. It is also catalogued as GLP-1 receptor agonist. Identity was confirmed as RS-SEM-1 on lot SEM5-0803 by LC-MS/MS.
Which strengths of RS-SEM-1 are stocked, and what do they cost?
RS-SEM-1 is stocked in 5 strengths: 5 mg at $70.00, 10 mg at $86.80, 20 mg at $151.20, 30 mg at $182.00, 50 mg at $224.00. That is $14.00 per mg at 5 mg and $4.48 per mg at 50 mg. The compound is the same in every vial; the strength is the mass it contains.
Handling RS-SEM-1
One sealed vial per unit ordered, labelled with the compound name, the strength and the lot number, and shipped from the US with tracking. The lot number on the label is what opens its certificate — lot SEM5-0803 is COA7591, and any lot can be checked on the verify page.
For laboratory research use only. Not for human or veterinary use.
